Abstract: Decades of advocacy and fundraising by organizations like MAPS, and the work of dedicated academics and scientists has led to a ‘renaissance’ of research into the benefits of psychedelics. This new wave of psychedelic research has shown promising results. We’ve learned psilocybin can have anti-depressant and anti-anxiety effects that last for several months. It also appears to be helpful in the treatment of depression and anxiety in people who are terminally ill. And, for nicotine and alcohol dependence. Psilocybin may also increase the brain’s ability to create new emotional and information pathways.
Psilocybin, or ‘magic mushrooms’, belongs to a group of drugs called psychedelics.2
It’s usually eaten fresh, cooked or brewed into a tea.
Psilocybin has been around for a long time, and has been used by some Indigenous communities around the world for over 1000 years.3
In fact, some researchers believe rock paintings in Western Australia show psilocybin use in Indigenous ceremonies over 10,000 years ago.4
Psychedelics can cause changes in mood, perception and thoughts.
In the 1950s and 60s scientists became interested in how these effects might help people experiencing mental illness.2, 3
They began to study psychedelics to treat conditions including:
But in the late 60s, the US banned all psychedelics.3, 5 And the world, including Australia, soon followed suit.6
So, despite promising findings, psychedelic research ended abruptly in the 70s.3
But that’s changing.
Decades of advocacy and fundraising by organizations like MAPS, and the work of dedicated academics and scientists has led to a ‘renaissance’ of research into the benefits of psychedelics in Australia and overseas.
This new wave of psychedelic research has shown promising results.
We’ve learned psilocybin can have anti-depressant and anti-anxiety effects that last for several months.7
It also appears to be helpful in the treatment of depression and anxiety in people who are terminally ill. And, for nicotine and alcohol dependence.3, 8
Psilocybin may also increase the brain’s ability to create new emotional and information pathways.8
While we’re beginning to understand psilocybin’s potential, there’s also risks.
Psilocybin may worsen the symptoms of certain conditions like personality disorders and schizophrenia.3
We also know some physical health conditions, like heart and liver disease, increase the chance of negative side-effects.3
Psychedelic therapy should always take place under professional supervision to reduce risk.
In a clinical setting, a pre-determined and controlled dose of psilocybin is given to the patient under the supervision of a medical professional. Because the patient is in a therapeutic space and the dose is known, it is unlikely there will be a bad reaction.9
When taking magic mushrooms recreationally, it can be hard to know how strong the dose is and whether there are other contaminants from the environment. It can also be hard to know how a person’s surroundings might affect their experience. This can make it more likely that a bad trip will occur.
And, there’s the risk of confusing magic mushrooms with certain types of poisonous mushrooms, which look very similar.10
In 2021, the Australian Government announced $15 million worth of grants to researchers studying the mental health benefits of psychedelic drugs such as psilocybin, as well as other non-psychedelic drugs such as MDMA and ketamine.11
And last year Australia became home to the Psychae Institute, a global psychedelic research institute in Melbourne.12
Several clinical trials are underway in Australia studying:
From July 1, 2023, if a general practitioner (GP) thinks that psilocybin-assisted therapy may be an appropriate treatment option, they can refer you to a psychiatrist who is an authorized prescriber.
But this will likely be a very small number of psychiatrists to begin with, and GPs might not know of available psychiatrists.
At this stage, psilocybin will also only be available for people with treatment-resistant depression. This is generally when someone hasn't responded well to antidepressant medications/treatments for their condition.
For more info on the regulation change and access requirements visit: Re-scheduling of psilocybin and MDMA in the Poisons Standard: questions and answers | Therapeutic Goods Administration (TGA)